Metabolism. Differential regulation of mTORC1 by leucine and glutamine.

Jewell JL, Kim YC, Russell RC, Yu FX, Park HW, Plouffe SW, Tagliabracci VS, Guan KL Science 2015 Jan 347 6218 194-8


Nutrient signaling to mTOR and cell growth.

Jewell JL, Guan KL Trends Biochem. Sci. 2013 May 38 5 233-42


Amino acid signalling upstream of mTOR.

Jewell JL, Russell RC, Guan KL Nat. Rev. Mol. Cell Biol. 2013 Mar 14 3 133-9


NLK phosphorylates Raptor to mediate stress-induced mTORC1 inhibition.

Yuan HX, Wang Z, Yu FX, Li F, Russell RC, Jewell JL, Guan KL Genes Dev. 2015 Nov 29 22 2362-76


Micro(RNA) Managing by mTORC1.

Jewell JL, Flores F, Guan KL Mol. Cell 2015 Feb 57 4 575-6


Rag GTPases are cardioprotective by regulating lysosomal function.

Kim YC, Park HW, Sciarretta S, Mo JS, Jewell JL, Russell RC, Wu X, Sadoshima J, Guan KL Nat Commun 2014 5 4241


Protein kinase A activates the Hippo pathway to modulate cell proliferation and differentiation.

Yu FX, Zhang Y, Park HW, Jewell JL, Chen Q, Deng Y, Pan D, Taylor SS, Lai ZC, Guan KL Genes Dev. 2013 Jun 27 11 1223-32


Regulation of the Hippo-YAP pathway by G-protein-coupled receptor signaling.

Yu FX, Zhao B, Panupinthu N, Jewell JL, Lian I, Wang LH, Zhao J, Yuan H, Tumaneng K, Li H, Fu XD, Mills GB, Guan KL Cell2012 Aug 150 4 780-91


Munc18c phosphorylation by the insulin receptor links cell signaling directly to SNARE exocytosis.

Jewell JL, Oh E, Ramalingam L, Kalwat MA, Tagliabracci VS, Tackett L, Elmendorf JS, Thurmond DC J. Cell Biol. 2011 Apr 193 1 185-99


Exocytosis mechanisms underlying insulin release and glucose uptake: conserved roles for Munc18c and syntaxin 4.

Jewell JL, Oh E, Thurmond DC Am. J. Physiol. Regul. Integr. Comp. Physiol. 2010 Mar 298 3 R517-31


The tyrosine phosphorylation of Munc18c induces a switch in binding specificity from syntaxin 4 to Doc2beta.

Jewell JL, Oh E, Bennett SM, Meroueh SO, Thurmond DC J. Biol. Chem. 2008 Aug 283 31 21734-46


Filamentous actin regulates insulin exocytosis through direct interaction with Syntaxin 4.

Jewell JL, Luo W, Oh E, Wang Z, Thurmond DC J. Biol. Chem. 2008 Apr 283 16 10716-26